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There are several options you can use to eliminate such artifacts.
Grid Resolution
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First, make sure your grid resolution Grid Resolution is not too low. If you have a simulation with less than 10 milliоn voxels, the flickering might be resolved by increasing the grid resolution and simulating again.
Render-time Solutions
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There are also many ways to reduce or completely resolve such flickering after the simulation is done, without having to simulate all over again.
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- [Mesh and Isosurface] changing the Isosurface Level option;
- [Isosurface only] changing the Isosurface Sampler from Linear to Spherical;
- [Mesh and Isosurface] enabling Input Grid Channel Smoothing;
- [Mesh only] enabling Mesh Smoothness and optionally enabling the Use Liquid Particles option;
- [Mesh only] adding a Relax modifier;.
Isosurface Level
Changing the Isosurface Level would help when in animation you see many pairs of droplets that keep connecting and disconnecting from one another.
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The recommended values for the smoothest result are all zeroes for the Threshold, Similarity and Random Variation options - this will produce strongest smoothing, evenly applied over the entire liquid grid evenly, without adding any random variation.
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